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Successful transdermal medications like nicotine patches or hormone replacement therapy work because these molecules have specific properties: theyre small, fat-soluble, and potent at very low doses

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No formal PRISMA methodology, risk-of-bias assessment, or evidence grading system was applied, as the aim of this work was to provide a critical narrative synthesis of the current evidence rather than a systematic quantitative assessment

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One of the most important statutes governing these cases is Section 600.2912b of the Michigan Compiled Laws, which outlines the notice requirements that must generally be satisfied before filing a medical malpractice lawsuit in Michigan